Open AccessIdentification of TEM-135 β-Lactamase in Neisseria gonorrhoeae Strains Carrying African and Toronto Plasmids in Argentina
Author(s) -
Ricardo Gianecini,
C Oviedo,
Ana Littvik,
Emilce Méndez,
Laura Piccoli,
S. Montibello,
Patricia Galarza
Publication year - 2014
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.03838-14
Subject(s) - neisseria gonorrhoeae , plasmid , microbiology and biotechnology , neisseriaceae , identification (biology) , biology , beta lactamase , gonorrhea , virology , antibiotics , escherichia coli , genetics , gene , botany , human immunodeficiency virus (hiv)
One hundred forty-three penicillinase-producingNeisseria gonorrhoeae (PPNG) isolates obtained in Argentina from 2008 and 2012 were examined to detectbla TEM-135 genes and to investigate plasmid profiles and multiantigen sequence types. Forty-two PPNG isolates were found to carry TEM-135, and two contained a new TEM derivative characterized as TEM-220. Thebla TEM-135 allele was carried by the Toronto/Rio and African plasmids. Molecular epidemiology revealed that twobla TEM-135 isolates were related to previously described isolates from Thailand and China, indicating a common evolutionary origin.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom