Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis
Author(s) -
Shahul Hameed P,
Suresh Solapure,
Kakoli Mukherjee,
Vrinda Nandi,
David Waterson,
Radha Krishan Shandil,
Meenakshi Balganesh,
Vasan K. Sambandamurthy,
Anand Kumar Raichurkar,
Abhijeet Deshpande,
Anirban Ghosh,
Disha Awasthy,
Gajanan Shanbhag,
Gulebahar Sheikh,
Helen McMiken,
Jayashree Puttur,
Jitendar Reddy,
Jim Werngren,
Jon Read,
Mahesh Kumar,
R Manjunatha,
Murugan Chinnapattu,
Prashanti Madhavapeddi,
Praveena Manjrekar,
Reetobrata Basu,
Sheshagiri Gaonkar,
Sreevalli Sharma,
Sven Hoffner,
Vaishali Humnabadkar,
Venkita Subbulakshmi,
Vijender Panduga
Publication year - 2014
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.03463-14
Subject(s) - tuberculosis , mycobacterium tuberculosis , structure–activity relationship , microbiology and biotechnology , atpase , biology , enzyme , virology , computational biology , chemistry , medicine , biochemistry , pathology , in vitro
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