Sequence Types 235, 111, and 132 Predominate among Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates in Croatia | Zendy

Marija Gužvinec | Zendy; Radosław Izdebski | Zendy; Iva Butić | Zendy; Marko Jelić | Zendy; Maja Abram | Zendy; Iva Košćak | Zendy; Anna Baraniak | Zendy; Waleria Hryniewicz | Zendy; Marek Gniadkowski | Zendy; Arjana Tambić Andrašević | Zendy

Open Access

Sequence Types 235, 111, and 132 Predominate among Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates in Croatia

Author(s) -

Marija Gužvinec,

Radosław Izdebski,

Iva Butić,

Marko Jelić,

Maja Abram,

Iva Košćak,

Anna Baraniak,

Waleria Hryniewicz,

Marek Gniadkowski,

Arjana Tambić Andrašević

Publication year - 2014

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.03116-14

Subject(s) - serotype , pseudomonas aeruginosa , biology , microbiology and biotechnology , multiple drug resistance , sequence (biology) , pseudomonadaceae , pseudomonadales , population , pseudomonas , sequence analysis , antibiotics , bacteria , gene , genetics , medicine , environmental health

A population analysis of 103 multidrug-resistant Pseudomonas aeruginosa isolates from Croatian hospitals was performed. Twelve sequence types (STs) were identified, with a predominance of international clones ST235 (serotype O11 [41%]), ST111 (serotype O12 [15%]), and ST132 (serotype O6 [11%]). Overexpression of the natural AmpC cephalosporinase was common (42%), but only a few ST235 or ST111 isolates produced VIM-1 or VIM-2 metallo-β-lactamases or PER-1 or GES-7 extended-spectrum β-lactamases.

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