Chicken Meat as a Reservoir of Colistin-Resistant Escherichia coli Strains Carrying mcr-1 Genes in South America | Zendy

Daniel F.M. Monte | Zendy; Andressa Mem | Zendy; Miriam R. Fernandes | Zendy; Louise Cerdeira | Zendy; Fernanda Esposito | Zendy; Júlia Arantes Galvão | Zendy; Bernadette Dora Gombossy de Melo Franco | Zendy; Nilton Lincopán | Zendy; Mariza Landgraf | Zendy

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Chicken Meat as a Reservoir of Colistin-Resistant Escherichia coli Strains Carrying mcr-1 Genes in South America

Author(s) -

Daniel F.M. Monte,

Andressa Mem,

Miriam R. Fernandes,

Louise Cerdeira,

Fernanda Esposito,

Júlia Arantes Galvão,

Bernadette Dora Gombossy de Melo Franco,

Nilton Lincopán,

Mariza Landgraf

Publication year - 2017

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02718-16

Subject(s) - mcr 1 , colistin , escherichia coli , plasmid , enterobacteriaceae , microbiology and biotechnology , biology , escherichia coli proteins , gene , antibiotics , genetics

The detection and rapid spread of colistin-resistant Enterobacteriaceae carrying the mcr-1 gene has created an urgent need to strengthen surveillance. In this study, eight clonally unrelated colistin-resistant Escherichia coli isolates carrying mcr-1 and bla CTX-M or bla CMY-2 genes were isolated from commercial chicken meat in Brazil. Most E. coli strains carried IncX4 plasmids, previously identified in human and animal isolates. These results highlight a new reservoir of mcr-1 -harboring E. coli strains in South America.

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