Escherichia coli Harboring mcr-1 in a Cluster of Liver Transplant Recipients: Detection through Active Surveillance and Whole-Genome Sequencing | Zendy

Nenad Macesic | Zendy; Sabrina Khan | Zendy; Marla J. Giddins | Zendy; Daniel E. Freedberg | Zendy; Susan Whittier | Zendy; Daniel A. Green | Zendy; E. Yoko Furuya | Zendy; Elizabeth C. Verna | Zendy; Medini K. Annavajhala | Zendy; Angela GomezSimmonds | Zendy; AnneCatrin Uhlemann | Zendy

Open Access

Escherichia coli Harboring mcr-1 in a Cluster of Liver Transplant Recipients: Detection through Active Surveillance and Whole-Genome Sequencing

Author(s) -

Nenad Macesic,

Sabrina Khan,

Marla J. Giddins,

Daniel E. Freedberg,

Susan Whittier,

Daniel A. Green,

E. Yoko Furuya,

Elizabeth C. Verna,

Medini K. Annavajhala,

Angela GomezSimmonds,

AnneCatrin Uhlemann

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02680-18

Subject(s) - mcr 1 , escherichia coli , colistin , plasmid , enterobacteriaceae infections , biology , microbiology and biotechnology , whole genome sequencing , cluster (spacecraft) , enterobacteriaceae , gene , genome , genetics , antibiotics , computer science , programming language

mcr-1 , a plasmid-associated gene for colistin resistance, was first described in China in 2015, but its spread in the United States is unknown. We report detection ofmcr-1 -carryingEscherichia coli ST117 in a cluster of three liver transplant recipients.

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