Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient | Zendy

Rainer Hartl | Zendy; Heidrun Kerschner | Zendy; Sarah Lepuschitz | Zendy; Werner Ruppitsch | Zendy; Franz Allerberger | Zendy; Petra Apfalter | Zendy

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Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient

Author(s) -

Rainer Hartl,

Heidrun Kerschner,

Sarah Lepuschitz,

Werner Ruppitsch,

Franz Allerberger,

Petra Apfalter

Publication year - 2017

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02623-16

Subject(s) - mcr 1 , escherichia coli , enterobacteriaceae , plasmid , colistin , microbiology and biotechnology , multiple drug resistance , escherichia coli proteins , gene , biology , enterobacteriaceae infections , genetics , drug resistance , antibiotics

Since colistin resistance based on the plasmid-encodedmcr-1 gene was first described, this resistance gene inEnterobacteriaceae has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation ofmcr-1 in a humanEscherichia coli strain cultured from a surveillance stool sample of an Austrian oncology patient.

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