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The antimicrobial activity of tebipenem and other carbapenem agents were testedin vitro against a set of recent clinical isolates responsible for urinary tract infection (UTI), as well as against a challenge set. Isolates were tested by reference broth microdilution and includedEscherichia coli (101 isolates),Klebsiella pneumoniae (208 isolates), andProteus mirabilis (103 isolates) species.

antimicrobial agents and chemotherapy

Antimicrobial Activity Evaluation of Tebipenem (SPR859), an Orally Available Carbapenem, against a Global Set of Enterobacteriaceae Isolates, Including a Challenge Set of Organisms