Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity | Zendy

Adel Malek | Zendy; Kelly A. McGlynn | Zendy; Samantha M. Taffner | Zendy; Lynn Fine | Zendy; Brenda Tesini | Zendy; Jun Wang | Zendy; Heba H. Mostafa | Zendy; Sharon Petry | Zendy; Archibald S. Perkins | Zendy; Paul Graman | Zendy; Dwight J. Hardy | Zendy; Nicole Pecora | Zendy

Open Access

Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity

Author(s) -

Adel Malek,

Kelly A. McGlynn,

Samantha M. Taffner,

Lynn Fine,

Brenda Tesini,

Jun Wang,

Heba H. Mostafa,

Sharon Petry,

Archibald S. Perkins,

Paul Graman,

Dwight J. Hardy,

Nicole Pecora

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02577-18

Subject(s) - enterobacter aerogenes , outbreak , intensive care unit , drug resistance , klebsiella pneumoniae , klebsiella , microbiology and biotechnology , medicine , population , carbapenem , incidence (geometry) , intensive care , biology , intensive care medicine , virology , antibiotics , escherichia coli , environmental health , biochemistry , physics , optics , gene

Klebsiella aerogenes is a nosocomial pathogen associated with drug resistance and outbreaks in intensive care units. In a 5-month period in 2017, we experienced an increased incidence of cultures for carbapenem-resistantK. aerogenes (CR-KA) from an adult cardiothoracic intensive care unit (CICU) involving 15 patients.

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