Complete Sequences of Multidrug Resistance Plasmids Bearing rmtD1 and rmtD2 16S rRNA Methyltransferase Genes | Zendy

Maria Fernanda Campagnari Bueno | Zendy; Gabriela Rodrigues Francisco | Zendy; Doroti de Oliveira Garcia | Zendy; Yohei Doi | Zendy

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Complete Sequences of Multidrug Resistance Plasmids Bearing rmtD1 and rmtD2 16S rRNA Methyltransferase Genes

Author(s) -

Maria Fernanda Campagnari Bueno,

Gabriela Rodrigues Francisco,

Doroti de Oliveira Garcia,

Yohei Doi

Publication year - 2016

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02562-15

Subject(s) - genetics , gene , biology , plasmid , multiple drug resistance , methyltransferase , allele , 16s ribosomal rna , integron , ribosomal rna , drug resistance , methylation

Complete nucleotide sequences were determined for two plasmids bearingrmtD group 16S rRNA methyltransferase genes. pKp64/11 was 78 kb in size, belonged to the IncL/M group, and harboredbla TEM-1b ,sul1 ,qacE Δ1 ,dfrA22 , andrmtD1 across two multidrug resistance regions (MRRs). pKp368/10 was 170 kb in size, belonged to the IncA/C group, and harboredacrB ,sul1 ,qacE Δ1 ,ant(3″)-Ia ,aac(6′)-Ib ,cat ,rmtD2 , andbla CTX-M-8 across three MRRs. ThermtD -containing regions shared a conserved motif, suggesting a common origin for the twormtD alleles.

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