Antimicrobial Resistance in Salmonella in the United States from 1948 to 1995 | Zendy

Daniel A. Tadesse | Zendy; Aparna Singh | Zendy; Shaohua Zhao | Zendy; Mary J. Bartholomew | Zendy; Niketta Womack | Zendy; Sherry Ayers | Zendy; Patricia I. Fields | Zendy; Patrick F. McDermott | Zendy

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Antimicrobial Resistance in Salmonella in the United States from 1948 to 1995

Author(s) -

Daniel A. Tadesse,

Aparna Singh,

Shaohua Zhao,

Mary J. Bartholomew,

Niketta Womack,

Sherry Ayers,

Patricia I. Fields,

Patrick F. McDermott

Publication year - 2016

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02536-15

Subject(s) - salmonella , antimicrobial , antibiotic resistance , resistance (ecology) , microbiology and biotechnology , medicine , biology , antibiotics , bacteria , genetics , ecology

We conducted a retrospective study of 2,149 clinicalSalmonella strains to help document the historical emergence of antimicrobial resistance. There were significant increases in resistance to older drugs, including ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, and tetracycline, which were most common inSalmonella enterica serotype Typhimurium. An increase in multidrug resistance was observed for each decade since the 1950s. These data help show howSalmonella evolved over the past 6 decades, after the introduction of new antimicrobial agents.

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