Characterization of the pJB12 Plasmid from Pseudomonas aeruginosa Reveals Tn 6352 , a Novel Putative Transposon Associated with Mobilization of the bla VIM-2 -Harboring In58 Integron | Zendy

João Botelho | Zendy; Filipa Grosso | Zendy; Luı́sa Peixe | Zendy

Open Access

Characterization of the pJB12 Plasmid from Pseudomonas aeruginosa Reveals Tn 6352 , a Novel Putative Transposon Associated with Mobilization of the bla _VIM-2 -Harboring In58 Integron

Author(s) -

João Botelho,

Filipa Grosso,

Luı́sa Peixe

Publication year - 2017

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02532-16

Subject(s) - integron , transposable element , plasmid , pseudomonas aeruginosa , biology , transposition (logic) , genetics , gene , microbiology and biotechnology , bacteria , genome , linguistics , philosophy

Thebla VIM-2 -carrying In58 integron has been linked to a chromosomal location in different bacterial species, includingPseudomonas aeruginosa . This work reports the first fully sequenced In58-harboring plasmid, which is significantly different from the two previously identifiedbla VIM-2 -carrying plasmids inP. aeruginosa .bla VIM-2 might have been acquired by transposition of Tn6352 , a novel transposon composed of the In58 and ISPa17 elements. The recognition of similar inverted repeat (IR) sites by ISPa17 reveals a common mobilization process associated with acquisition of thebla VIM-2 andbla VIM-1 genes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research