Antifungal Drugs Influence Neutrophil Effector Functions | Zendy

Frederic Ries | Zendy; Astrid Alflen | Zendy; Pamela Aranda Lopez | Zendy; H Beckert | Zendy; Matthias Theobald | Zendy; Hansjörg Schild | Zendy; Daniel Teschner | Zendy; Markus P. Radsak | Zendy

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Antifungal Drugs Influence Neutrophil Effector Functions

Author(s) -

Frederic Ries,

Astrid Alflen,

Pamela Aranda Lopez,

H Beckert,

Matthias Theobald,

Hansjörg Schild,

Daniel Teschner,

Markus P. Radsak

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02409-18

Subject(s) - degranulation , phagocytosis , effector , reactive oxygen species , immunology , biology , caspofungin , flow cytometry , microbiology and biotechnology , pharmacology , chemistry , fluconazole , biochemistry , antifungal , receptor

There is a growing body of evidence for immunomodulatory side effects of antifungal agents on different immune cells, e.g., T cells. Therefore, the aim of our study was to clarify these interactions with regard to the effector functions of polymorphonuclear neutrophils (PMN).

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