Open AccessComplete Nucleotide Sequences of Two bla KPC-2 -Bearing IncN Plasmids Isolated from Sequence Type 442 Klebsiella pneumoniae Clinical Strains Four Years Apart
Author(s) -
Paula Juliana PérezChaparro,
Louise Cerdeira,
Maíse Gomes Queiroz,
Clayton Pereira Silva de Lima,
Carlos Emílio Levy,
Mónica Pávez,
Nilton Lincopán,
Evonnildo Costa Gonçalves,
Elsa Masae Mamizuka,
Jorge Luiz Mello Sampaio,
Márcio Roberto Teixeira Nunes,
John Anthony McCulloch
Publication year - 2014
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02341-13
Subject(s) - klebsiella pneumoniae , plasmid , biology , enterobacteriaceae , microbiology and biotechnology , sequence (biology) , klebsiella infections , genetics , virology , gene , escherichia coli
We sequenced the oldest blaKPC-2-bearing plasmid isolated in Brazil and another plasmid also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), isolated 52 months later. Both plasmids present an IncN backbone and few acquired regions. Because the 2005 plasmid presented deletions and a truncated gene within Tn4401b compared to the 2009 plasmid, we can thus infer that IncN blaKPC-2-bearing plasmids pFCF1305 and pFCF3SP had a common ancestor circulating in Brazil prior to May 2005.
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