Activity of Ceftolozane-Tazobactam against a Broad Spectrum of Recent Clinical Anaerobic Isolates | Zendy

David R. Snydman | Zendy; L. A. McDermott | Zendy; N V Jacobus | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Activity of Ceftolozane-Tazobactam against a Broad Spectrum of Recent Clinical Anaerobic Isolates

Author(s) -

David R. Snydman,

L. A. McDermott,

N V Jacobus

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02253-13

Subject(s) - bacteroides fragilis , microbiology and biotechnology , tazobactam , bacteroides , prevotella , biology , anaerobic bacteria , fusobacterium , clostridium , antibiotics , bacteria , antibiotic resistance , imipenem , genetics

We evaluated in vitro activity of ceftolozane-tazobactam (TOL-TAZ), formerly CXA-201, against recent clinical anaerobic isolates with emphasis on the Bacteroides fragilis group. Ceftolozane-tazobactam showed good activity against B. fragilis species and intermediate to limited activity against other species of Bacteroides. Ceftolozane-tazobactam showed very good activity against Prevotella spp., Fusobacterium spp., and Propionibacterium spp., varying activities against Gram-positive cocci, and limited activity against Clostridium spp.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research