Indole-2-Carboxamides Are Active against Mycobacterium abscessus in a Mouse Model of Acute Infection
Author(s) -
Amit N. Pandya,
Pavan Kumar Prathipati,
Pooja Hegde,
Wěi Li,
Kyle F. Graham,
Subhra Mandal,
Kristen M. Drescher,
Christopher J. Destache,
Diane Ordway,
Mary Jackson,
E. Jeffrey North
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02245-18
Subject(s) - mycobacterium abscessus , indole test , microbiology and biotechnology , medicine , mycobacterium , biology , pathology , tuberculosis , biochemistry
Nontuberculous mycobacteria (NTM) pathogens particularly infect patients with structural lung disorders. We previously reported novel indole-2-carboxamides (ICs) that are active against a wide panel of NTM pathogens.
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