Roles of Efflux Pumps from Different Superfamilies in the Surface-Associated Motility and Virulence of Acinetobacter baumannii ATCC 17978 | Zendy

María Pérez−Varela | Zendy; Jordi Corral | Zendy; Jesús Aranda | Zendy; Jordi Barbé | Zendy

Open Access

Roles of Efflux Pumps from Different Superfamilies in the Surface-Associated Motility and Virulence of Acinetobacter baumannii ATCC 17978

Author(s) -

María Pérez−Varela,

Jordi Corral,

Jesús Aranda,

Jordi Barbé

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02190-18

Subject(s) - acinetobacter baumannii , efflux , virulence , microbiology and biotechnology , major facilitator superfamily , pathogen , biology , opportunistic pathogen , acinetobacter , motility , antibiotic resistance , bacteria , antibiotics , mutant , genetics , pseudomonas aeruginosa , gene

Although the relationship betweenAcinetobacter baumannii efflux pumps and antimicrobial resistance is well documented, less is known about the involvement of these proteins in the pathogenicity of this nosocomial pathogen. In previous work, we identified the AbaQ major facilitator superfamily (MFS) efflux pump and demonstrated its participation in the motility and virulence ofA. baumannii .

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