High Prevalence of Antibiotic Resistance and Molecular Characterization of Integrons among Shigella Isolates in Eastern China | Zendy

Yun Shen | Zendy; Huimin Qian | Zendy; Gong Jun-jun | Zendy; Feifei Deng | Zendy; Chen Dong | Zendy; Lu Zhou | Zendy; Hongxiong Guo | Zendy

Open Access

High Prevalence of Antibiotic Resistance and Molecular Characterization of Integrons among Shigella Isolates in Eastern China

Author(s) -

Yun Shen,

Huimin Qian,

Gong Jun-jun,

Feifei Deng,

Chen Dong,

Lu Zhou,

Hongxiong Guo

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02102-12

Subject(s) - integron , shigella , shigella flexneri , microbiology and biotechnology , antibiotic resistance , biology , antibiotics , antimicrobial , salmonella , bacteria , gene , escherichia coli , genetics

A total of 747Shigella isolates were collected from hospitals in Jiangsu Province of China. Susceptibilities to antimicrobials and integrons were tested. A total of 78.3% ofS. flexneri isolates and a total of 74.3%S. sonei isolates were resistant to at least three antibiotics. Of theShigella isolates, 74.7% had integron I and 82.6% had integron II. The conjunction of the high prevalence of integrons inShigella and high resistance to antimicrobials will lead to rapid dissemination of resistant genes in this region.

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