Role of OmpA in the Multidrug Resistance Phenotype of Acinetobacter baumannii | Zendy

Younes Smani | Zendy; Anna Fàbrega | Zendy; Ignasi Roca | Zendy; Viviana Sánchez-Encinales | Zendy; Jordi Vilà | Zendy; Jerónimo Pachón | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Role of OmpA in the Multidrug Resistance Phenotype of Acinetobacter baumannii

Author(s) -

Younes Smani,

Anna Fàbrega,

Ignasi Roca,

Viviana Sánchez-Encinales,

Jordi Vilà,

Jerónimo Pachón

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02101-13

Subject(s) - acinetobacter baumannii , microbiology and biotechnology , nalidixic acid , multiple drug resistance , aztreonam , biology , antimicrobial , phenotype , chloramphenicol , antibiotic resistance , neisseriaceae , acinetobacter , antibiotics , gene , bacteria , pseudomonas aeruginosa , genetics , imipenem

Acinetobacter baumannii has emerged as a nosocomial pathogen with an increased prevalence of multidrug-resistant strains. The role of the outer membrane protein A (OmpA) in antimicrobial resistance remains poorly understood. In this report, disruption of the ompA gene led to decreased MICs of chloramphenicol, aztreonam, and nalidixic acid. We have characterized, for the first time, the contribution of OmpA in the antimicrobial resistance phenotype of A. baumannii.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research