Emergence of the 16S rRNA Methylase RmtG in an Extended-Spectrum-β-Lactamase-Producing and Colistin-Resistant Klebsiella pneumoniae Isolate in Chile
Author(s) -
Laurent Poirel,
Jaime Labarca,
Helia BelloToledo,
María Luisa Rioseco,
Sandrine Bernabeu,
Patrice Nordmann
Publication year - 2013
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02059-13
Subject(s) - klebsiella pneumoniae , colistin , microbiology and biotechnology , 16s ribosomal rna , biology , klebsiella , methyltransferase , enterobacteriaceae , bacteria , antibiotics , escherichia coli , genetics , gene , methylation
While carbapenemases are disseminating worldwide in Enterobacteriaceae, and particularly in Escherichia and Klebsiella pneumoniae ([1][1]), therapeutic options increasingly rely on very few choices ([2][2]). Although colistin and tigecycline are now considered last-resort antibiotics for treating
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