Prevalence of Colistin Resistance Gene mcr-1 and Absence of mcr-2 in Escherichia coli Isolated from Healthy Food-Producing Animals in Japan | Zendy

Michiko Kawanishi | Zendy; Hitoshi Abo | Zendy; Manao Ozawa | Zendy; Mariko Uchiyama | Zendy; Takahiro Shirakawa | Zendy; Satowa Suzuki | Zendy; Ayaka Shima | Zendy; Akifumi Yamashita | Zendy; Tsuyoshi Sekizuka | Zendy; Kengo Kato | Zendy; Makoto Kuroda | Zendy; Ryoji Koike | Zendy; Mayumi Kijima | Zendy

Open Access

Prevalence of Colistin Resistance Gene mcr-1 and Absence of mcr-2 in Escherichia coli Isolated from Healthy Food-Producing Animals in Japan

Author(s) -

Michiko Kawanishi,

Hitoshi Abo,

Manao Ozawa,

Mariko Uchiyama,

Takahiro Shirakawa,

Satowa Suzuki,

Ayaka Shima,

Akifumi Yamashita,

Tsuyoshi Sekizuka,

Kengo Kato,

Makoto Kuroda,

Ryoji Koike,

Mayumi Kijima

Publication year - 2016

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02057-16

Subject(s) - mcr 1 , escherichia coli , colistin , microbiology and biotechnology , biology , gene , enterobacteriaceae , sequence homology , antimicrobial , homology (biology) , genetics , peptide sequence

We screened mcr-1 and mcr-2 genes in 9,306 Escherichia coli strains isolated from healthy animals in the Japanese Veterinary Antimicrobial Resistance Monitoring (JVARM) system. mcr-1 was detected in 39 strains (5, 20, and 14 strains isolated from cattle, swine, and broilers, respectively), whereas mcr-2 was not detected. mcr-2 was also not detected with the investigation sequence homology search against our curated GenEpid-J database.

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