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Infections caused by the coexistence ofCandida glabrata echinocandin-resistant and echinocandin-susceptible cells may be possible, and the detection ofFKS mutants when the proportions ofFKS mutants are underrepresented poses a problem. We assessed the role of EUCAST and methods directly performed on positive blood cultures—Etest (ETDIR ) and anidulafungin-containing agar plate assays—for detecting resistance inC. glabrata isolates containing different amounts of echinocandin-susceptible and -resistantCandida glabrata isolates.

Detection of Echinocandin-Resistant Candida glabrata in Blood Cultures Spiked with Different Percentages of FKS2 Mutants