z-logo
open-access-imgOpen Access
Impact of Antifungal Compounds on Viability and Anti- Aspergillus Activity of Human Natural Killer Cells
Author(s) -
Stanislaw Schmidt,
Ralf Schubert,
Lars Tramsen,
Thomas Lehrnbecher
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01993-18
Subject(s) - aspergillosis , antifungal , natural killer cell , aspergillus , adoptive cell transfer , immunology , in vitro , biology , haematopoiesis , aspergillus fumigatus , microbiology and biotechnology , hematopoietic stem cell transplantation , hematopoietic cell , immune system , stem cell , cytotoxicity , t cell , biochemistry , genetics
Despite the availability of new antifungal compounds, invasive aspergillosis carries high morbidity and mortality in hematopoietic stem cell transplant recipients.In vitro studies and animal models suggest that the adoptive transfer of natural killer (NK) cells might be a promising immunotherapeutic option in this setting.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom