Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae | Zendy

Henrietta Abodakpi | Zendy; KaiTai Chang | Zendy; Song Gao | Zendy; Ana María SánchezDíaz | Zendy; Rafael Cantón | Zendy; Vincent H. Tam | Zendy

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Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

Author(s) -

Henrietta Abodakpi,

KaiTai Chang,

Song Gao,

Ana María SánchezDíaz,

Rafael Cantón,

Vincent H. Tam

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01906-18

Subject(s) - piperacillin/tazobactam , dosing , piperacillin , enterobacteriaceae , tazobactam , antibiotics , microbiology and biotechnology , cephalosporin , beta lactamase inhibitors , medicine , enterobacteriaceae infections , biology , escherichia coli , bacteria , pharmacology , antibiotic resistance , imipenem , pseudomonas aeruginosa , genetics , gene

Piperacillin-tazobactam has been proposed as an alternative to carbapenems for the treatment of infections caused by extended-spectrum-β-lactamase (ESBL)-producingEnterobacteriaceae . However, limited understanding of optimal dosing strategies for this combination may curtail its utility.

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