Open AccessInhibition of Yeast-to-Hypha Transition and Virulence of Candida albicans by 2-Alkylaminoquinoline Derivatives
Author(s) -
Lili Meng,
He Zhao,
Shuo Zhao,
Xiuyun Sun,
Min Zhang,
Yinyue Deng
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01891-18
Subject(s) - candida albicans , corpus albicans , hypha , microbiology and biotechnology , virulence , biology , yeast , cytotoxicity , biochemistry , gene , in vitro
A rapid increase inCandida albicans infection and drug resistance has caused an emergent need for new clinical strategies against this fungal pathogen. In this study, we evaluated the inhibitory activity of a series of 2-alkylaminoquinoline derivatives againstC. albicans isolates.
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