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The activity of the siderophore cephalosporin cefiderocol is targeted against carbapenem-resistant Gram-negative bacteria. In this study, the activity of cefiderocol against characterized carbapenem-resistantAcinetobacter baumannii complex,Stenotrophomonas maltophilia ,Pseudomonas aeruginosa , andEnterobacteriaceae strains was determined by microdilution in iron-depleted Mueller-Hinton broth.

antimicrobial agents and chemotherapy

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and <i>Enterobacteriaceae</i> with Defined Extended-Spectrum β-Lactamases and Carbapenemases

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases