ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases | Zendy

Michael R. Jacobs | Zendy; Ayman M. Abdelhamed | Zendy; Caryn E. Good | Zendy; Daniel D. Rhoads | Zendy; Kristine M. Hujer | Zendy; Andrea M. Hujer | Zendy; Tatiana Domitrovic | Zendy; Susan D. Rudin | Zendy; Sandra S. Richter | Zendy; David van Duin | Zendy; Barry N. Kreiswirth | Zendy; Chris Greco | Zendy; Derrick E. Fouts | Zendy; Robert A. Bonomo | Zendy

Open Access

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases

Author(s) -

Michael R. Jacobs,

Ayman M. Abdelhamed,

Caryn E. Good,

Daniel D. Rhoads,

Kristine M. Hujer,

Andrea M. Hujer,

Tatiana Domitrovic,

Susan D. Rudin,

Sandra S. Richter,

David van Duin,

Barry N. Kreiswirth,

Chris Greco,

Derrick E. Fouts,

Robert A. Bonomo

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01801-18

Subject(s) - stenotrophomonas maltophilia , acinetobacter baumannii , cephalosporin , microbiology and biotechnology , siderophore , acinetobacter , enterobacteriaceae , biology , stenotrophomonas , carbapenem , pseudomonas aeruginosa , bacteria , pseudomonas , antibiotics , escherichia coli , biochemistry , genetics , gene

The activity of the siderophore cephalosporin cefiderocol is targeted against carbapenem-resistant Gram-negative bacteria. In this study, the activity of cefiderocol against characterized carbapenem-resistantAcinetobacter baumannii complex,Stenotrophomonas maltophilia ,Pseudomonas aeruginosa , andEnterobacteriaceae strains was determined by microdilution in iron-depleted Mueller-Hinton broth.

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