Dissemination of bla KPC-2 by the Spread of Klebsiella pneumoniae Clonal Complex 258 Clones (ST258, ST11, ST437) and Plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae Species in Brazil
Author(s) -
Leonardo Neves Andrade,
Tânia Curião,
Joseane Cristina Ferreira,
Juliana Mucedola Longo,
Eduardo Carneiro Clímaco,
Roberto Martínez,
Fernando BellissimoRodrigues,
Aníbal Basile-Filho,
Marco Antônio Evaristo,
Pedro Fernandez Del Peloso,
Vanessa Bley Ribeiro,
Afonso Luís Barth,
Milena Cristina Paula,
Fernando Baquero,
Rafael Cantón,
Ana Lúcia da Costa Darini,
Teresa M. Coque
Publication year - 2011
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01783-10
Subject(s) - citrobacter freundii , klebsiella pneumoniae , enterobacter cloacae , enterobacteriaceae , plasmid , microbiology and biotechnology , biology , outbreak , serratia marcescens , colonization , enterobacteriaceae infections , gene , virology , escherichia coli , genetics
This article reports the spread of bla(KPC-2) in the Sao Paulo and Rio de Janeiro states, facilitated by globally spread K. pneumoniae clonal complex 258 (CC258) clones (ST258, ST11, and ST437) and a diversity of plasmids (IncFII, IncN, and IncL/M, two untypeable plasmids carrying Tn4401a or Tn4401b) successfully disseminated among species of the Enterobacteriaceae (Enterobacter cloacae, Serratia marcescens, and Citrobacter freundii). It also constitutes the first description of sequence type 258 (ST258) in Brazil, which was associated with a nosocomial hospital outbreak in Ribeirao Preto city.
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