An IncR Plasmid Harbored by a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Strain Possesses Five Tandem Repeats of the bla KPC-2 ::NTE KPC -Id Fragment | Zendy

Ning Dong | Zendy; Lizhang Liu | Zendy; Rong Zhang | Zendy; Kaichao Chen | Zendy; Miaomiao Xie | Zendy; Edward WaiChi Chan | Zendy; Sheng Chen | Zendy

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An IncR Plasmid Harbored by a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Strain Possesses Five Tandem Repeats of the bla _KPC-2 ::NTE _KPC -Id Fragment

Author(s) -

Ning Dong,

Lizhang Liu,

Rong Zhang,

Kaichao Chen,

Miaomiao Xie,

Edward WaiChi Chan,

Sheng Chen

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01775-18

Subject(s) - plasmid , klebsiella pneumoniae , microbiology and biotechnology , biology , virulence , virology , enterobacteriaceae , tandem repeat , strain (injury) , carbapenem , klebsiella infections , homologous recombination , genetics , escherichia coli , gene , genome , antibiotics , anatomy

Completed sequences of three plasmids from a carbapenem-resistant hypervirulentKlebsiella pneumoniae isolate, SH9, were obtained. In addition to the pLVPK-like virulence-conferring plasmid (pVir-CR-HvKP_SH9), the two multidrug-resistant plasmids (pKPC-CR-HvKP4_SH9 and pCTX-M-CR-HvKP4_SH9) were predicted to originate from a single pKPC-CR-HvKP4-like multireplicon plasmid through homologous recombination.

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