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The nucleotide sequences of three IncU plasmids fromAeromonas spp. isolated from ornamental fish are described. They had a typical IncU backbone for plasmid replication and maintenance functions, but conjugative transfer modules were disrupted. The geneqnrS2 was inserted intompR as a mobile insertion cassette. Novel Tn3 family transposons carrying putative toxin-antitoxin and plasmid stability genes were identified. The study demonstrates high plasticity of IncU plasmids from aquatic environments.

antimicrobial agents and chemotherapy

Complete Sequences of IncU Plasmids Harboring Quinolone Resistance Genes qnrS2 and aac(6 ′ )-Ib-cr in Aeromonas spp. from Ornamental Fish