In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium | Zendy

Hamid Badali | Zendy; Sadegh Khodavaisy | Zendy; Hamed Fakhim | Zendy; Sybren de Hoog | Zendy; Jacques F. Meis | Zendy; Anuradha Chowdhary | Zendy

Open Access

In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium

Author(s) -

Hamid Badali,

Sadegh Khodavaisy,

Hamed Fakhim,

Sybren de Hoog,

Jacques F. Meis,

Anuradha Chowdhary

Publication year - 2015

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01733-15

Subject(s) - anidulafungin , posaconazole , voriconazole , caspofungin , itraconazole , fluconazole , amphotericin b , antifungal , in vitro , pharmacology , biology , microbiology and biotechnology , medicine , biochemistry

In vitro susceptibilities of a worldwide collection of molecularly identified Phaeoacremonium strains (n = 43) belonging to seven species and originating from human and environmental sources were determined for eight antifungal drugs. Voriconazole had the lowest geometric mean MIC (0.35 μg/ml), followed by posaconazole (0.37 μg/ml), amphotericin B (0.4 μg/ml), and isavuconazole (1.16 μg/ml). Caspofungin, anidulafungin, fluconazole, and itraconazole had no activity.

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