Capsular Type and Antibiotic Resistance in Streptococcus agalactiae Isolates from Patients, Ranging from Newborns to the Elderly, with Invasive Infections | Zendy

Somay Yamagata Murayama | Zendy; Chizuko Seki | Zendy; Hiroshi Sakata | Zendy; Katsuhiko Sunaoshi | Zendy; Eiichi Nakayama | Zendy; Satoshi Iwata | Zendy; Keisuke Sunakawa | Zendy; Kimiko Ubukata | Zendy

Open Access

Capsular Type and Antibiotic Resistance in Streptococcus agalactiae Isolates from Patients, Ranging from Newborns to the Elderly, with Invasive Infections

Author(s) -

Somay Yamagata Murayama,

Chizuko Seki,

Hiroshi Sakata,

Katsuhiko Sunaoshi,

Eiichi Nakayama,

Satoshi Iwata,

Keisuke Sunakawa,

Kimiko Ubukata

Publication year - 2009

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01716-08

Subject(s) - streptococcus agalactiae , microbiology and biotechnology , levofloxacin , biology , streptococcus suis , antibiotics , streptococcaceae , antibiotic resistance , streptococcus , antimicrobial , virology , gene , bacteria , virulence , genetics

Streptococcus agalactiae isolates (n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser(81)Leu in the gyrA gene and Ser(79)Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.

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