Genetic Mechanisms behind the Spread of Reduced Susceptibility to Azithromycin in Shigella Strains Isolated from Men Who Have Sex with Men in Québec, Canada
Author(s) -
Khadidja Yousfi,
Christiane Gaudreau,
Pierre A. Pilon,
Brigitte Lefebvre,
Matthew G. Walker,
Éric Fournier,
Florence Doualla Bell,
Christine Martineau,
Jean Longtin,
Sadjia Békal
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01679-18
Subject(s) - shigella , shigella flexneri , azithromycin , biology , shigella sonnei , microbiology and biotechnology , shigellosis , serotype , enterobacteriaceae , virology , plasmid , genetics , antibiotics , salmonella , gene , bacteria , escherichia coli
We analyzed 254Shigella species isolates collected in Québec, Canada, during 2013 and 2014. Overall, 23.6% of isolates showed reduced susceptibility to azithromycin (RSA) encoded bymphA (11.6%),ermB (1.7%), or both genes (86.7%).
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