Open AccessIn Vitro Activity of Azithromycin against Nontyphoidal Salmonella enterica
Author(s) -
Marianne Gunell,
Pirkko Kotilainen,
Jari Jalava,
Pentti Huovinen,
Anja Siitonen,
Antti Hakanen
Publication year - 2010
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01678-09
Subject(s) - salmonella enterica , azithromycin , microbiology and biotechnology , salmonella , in vitro , biology , virology , antibiotics , bacteria , biochemistry , genetics
The in vitro activity of azithromycin against 1,237 nontyphoidal Salmonella enterica isolates collected from Finnish patients between 2003 and 2008 was investigated. Only 24 (1.9%) of the isolates tested and 15 (5.1%) of the 294 isolates with reduced fluoroquinolone susceptibility had azithromycin MICs of >or=32 microg/ml. These data show that azithromycin has good in vitro activity against nontyphoidal S. enterica, and thus, it may be a good candidate for clinical treatment studies of salmonellosis.
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