A Loop-Mediated Isothermal Amplification Assay Targeting Neisseria gonorrhoeae penA -60.001 | Zendy

Ken Shimuta | Zendy; Shuichi Nakayama | Zendy; Hideyuki Takahashi | Zendy; Makoto Ohnishi | Zendy

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A Loop-Mediated Isothermal Amplification Assay Targeting Neisseria gonorrhoeae penA -60.001

Author(s) -

Ken Shimuta,

Shuichi Nakayama,

Hideyuki Takahashi,

Makoto Ohnishi

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01663-19

Subject(s) - neisseria gonorrhoeae , loop mediated isothermal amplification , neisseriaceae , microbiology and biotechnology , ceftriaxone , gonorrhea , gonococcal infection , virology , biology , medicine , antibiotics , sexually transmitted disease , syphilis , genetics , human immunodeficiency virus (hiv) , dna

Ceftriaxone (CRO) is widely used as the first-line treatment for gonococcal infections. However, CRO-resistantNeisseria gonorrhoeae strains carrying mosaicpenA -60.001 have emerged recently and disseminated worldwide. To meet the urgent need to detect these strains, we report here a loop-mediated isothermal amplification (LAMP) assay system that targetsN. gonorrhoeae penA -60.001.

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