Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients | Zendy

Xuemei Wu | Zendy; Cornelius J. Clancy | Zendy; Ryan Rivosecchi | Zendy; Wenchen Zhao | Zendy; Ryan K. Shields | Zendy; Rachel V Marini | Zendy; Raman Venkataramanan | Zendy; M. Hong Nguyen | Zendy

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Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients

Author(s) -

Xuemei Wu,

Cornelius J. Clancy,

Ryan Rivosecchi,

Wenchen Zhao,

Ryan K. Shields,

Rachel V Marini,

Raman Venkataramanan,

M. Hong Nguyen

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01643-18

Subject(s) - mucorales , pharmacokinetics , medicine , posaconazole , organ transplantation , voriconazole , clinical trial , aspergillosis , intensive care medicine , pharmacology , transplantation , mucormycosis , antifungal , surgery , immunology , dermatology

Isavuconazole may be useful in treating and preventing fungal infections in solid-organ transplant (SOT) recipients due to its safety profile and activity againstAspergillus and someMucorales . Isavuconazole has favorable pharmacokinetics based on clinical trials in various patient populations, but data are limited in SOT recipients.

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