In Vitro Activities of Eight Antifungal Drugs against 106 Waterborne and Cutaneous Exophiala Species | Zendy

Mohammad Javad Najafzadeh | Zendy; M. Saradeghi Keisari | Zendy; Vânia Aparecida Vicente | Zendy; Peiying Feng | Zendy; Seyyed Ali Akbar Shamsian | Zendy; Ali RezaeiMatehkolaei | Zendy; Sybren de Hoog | Zendy; Ilse Curfs-Breuker | Zendy; Jacques F. Meis | Zendy

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In Vitro Activities of Eight Antifungal Drugs against 106 Waterborne and Cutaneous Exophiala Species

Author(s) -

Mohammad Javad Najafzadeh,

M. Saradeghi Keisari,

Vânia Aparecida Vicente,

Peiying Feng,

Seyyed Ali Akbar Shamsian,

Ali RezaeiMatehkolaei,

Sybren de Hoog,

Ilse Curfs-Breuker,

Jacques F. Meis

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01629-13

Subject(s) - voriconazole , posaconazole , caspofungin , micafungin , itraconazole , amphotericin b , fluconazole , microbiology and biotechnology , in vitro , antifungal , pharmacology , biology , chemistry , biochemistry

The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.25 μg/ml; micafungin, 1 μg/ml; voriconazole, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 8 μg/ml; amphotericin B, 16 μg/ml; fluconazole, 64 μg/ml.

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