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Whole-Genome Sequencing To Identify Drivers of Carbapenem-Resistant Klebsiella pneumoniae Transmission within and between Regional Long-Term Acute-Care Hospitals
Author(s) -
Jennifer Han,
Zena Lapp,
Frederic D. Bushman,
Ebbing Lautenbach,
Ellie J. C. Goldstein,
Lisa M. Mattei,
Casey E. Hofstaedter,
Dorothy Kim,
Irving Nachamkin,
Charles Garrigan,
Tanya Jain,
Warren B. Bilker,
Hannah Wolford,
Rachel B. Slayton,
Jacqueleen Wise,
Pam Tolomeo,
Evan S. Snitkin
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01622-19
Subject(s) - klebsiella pneumoniae , carbapenem , transmission (telecommunications) , whole genome sequencing , microbiology and biotechnology , genome , carbapenem resistant enterobacteriaceae , biology , medicine , gene , genetics , antibiotics , escherichia coli , computer science , telecommunications
Carbapenem-resistantKlebsiella pneumoniae (CRKP) is an antibiotic resistance threat of the highest priority. Given the limited treatment options for this multidrug-resistant organism (MDRO), there is an urgent need for targeted strategies to prevent transmission.

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