Prospective Investigation of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Community-Associated Methicillin-Resistant Staphylococcus aureus Infections | Zendy

Loren G. Miller | Zendy; Jennifer Tan | Zendy; Samantha J. Eells | Zendy; Esther Benitez | Zendy; Allen B. Radner | Zendy

Open Access

Prospective Investigation of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Community-Associated Methicillin-Resistant Staphylococcus aureus Infections

Author(s) -

Loren G. Miller,

Jennifer Tan,

Samantha J. Eells,

Esther Benitez,

Allen B. Radner

Publication year - 2011

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01608-10

Subject(s) - mupirocin , hexachlorophene , medicine , staphylococcus aureus , staphylococcal skin infections , antibiotics , regimen , skin infection , methicillin resistant staphylococcus aureus , staphylococcal infections , micrococcaceae , prospective cohort study , microbiology and biotechnology , antibacterial agent , biology , chemistry , organic chemistry , bacteria , genetics

Recurrent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens. We prospectively evaluated 31 patients with recurrent CA-MRSA skin infections who received nasal mupirocin, topical hexachlorophene body wash, and an oral anti-MRSA antibiotic. The mean number of MRSA infections after the intervention decreased significantly from baseline (0.03 versus 0.84 infections/month, P = <0.0001). This regimen appears promising at preventing recurrent CA-MRSA infections.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research