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In Vitro Activities of β-Lactam–β-Lactamase Inhibitor Antimicrobial Agents against Cystic Fibrosis Respiratory Pathogens
Author(s) -
Lindsay J. Caverly,
Theodore Spilker,
Linda M. Kalikin,
Terri Stillwell,
Carol Young,
David B. Huang,
John J. LiPuma
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01595-19
Subject(s) - cystic fibrosis , antimicrobial , microbiology and biotechnology , medicine , in vitro , respiratory system , respiratory disease , lactam , pharmacology , biology , lung , chemistry , biochemistry , stereochemistry
We tested thein vitro activities of ceftazidime-avibactam, ceftolozane-tazobactam, meropenem-vaborbactam, piperacillin-tazobactam, and 11 other antimicrobial agents against 420Burkholderia ,Achromobacter ,Stenotrophomonas , andPandoraea strains, 89% of which were cultured from respiratory specimens from persons with cystic fibrosis.

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