Determination of the Genetic Support for tet (W) in Oral Bacteria
Author(s) -
A. Villedieu,
Adam P. Roberts,
Elaine Allan,
Haitham Hussain,
R. McNab,
David A. Spratt,
Michael A. Wilson,
Peter Mullany
Publication year - 2007
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01587-06
Subject(s) - transposase , bacteria , efflux , gene , microbiology and biotechnology , genetics , biology , oral cavity , insertion sequence , dna , antibacterial agent , transposable element , medicine , genome , orthodontics
The DNA sequence flanking a tet(W) gene in an oral Rothia sp. was determined. The gene was linked to two different transposases, and these were flanked by two almost identical mef (macrolide efflux) genes. This structure was found in 4 out of 20 tet(W)-containing oral bacteria investigated.
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