Open AccessOccurrence of ST23 Complex Phylogroup A Escherichia coli Isolates Producing Extended-Spectrum AmpC β-Lactamase in a French Hospital
Author(s) -
Lise Crémet,
Nathalie Caroff,
Cécile Giraudeau,
Sandie Dauvergne,
Didier Lepelletier,
Alain Reynaud,
Stéphane Corvec
Publication year - 2010
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01580-09
Subject(s) - escherichia coli , microbiology and biotechnology , phylogenetic tree , biology , enterobacteriaceae , beta lactamase , genetics , gene
Extended-spectrum AmpC β-lactamase (ESAC)Escherichia coli producers were investigated over a 5-year period. Eleven isolates presenting a strongampC promoter and different strategic AmpC mutations, including two newly described modifications (A292V and an L-A-A insertion at 295), were characterized. All the isolates belonged to phylogenetic group A and to the ST23 complex.