Characterization of a Novel Composite Staphylococcal Cassette Chromosome mec (SCC mec -SCC cad / ars / cop ) in the Neonatal Sepsis-Associated Staphylococcus capitis Pulsotype NRCS-A | Zendy

Patrícia Martins-Simões | Zendy; JeanPhilippe Rasigade | Zendy; Hajar Lemriss | Zendy; Marine Butin | Zendy; Christophe Ginévra | Zendy; Sanaâ Lemriss | Zendy; Richard V. Goering | Zendy; Azeddine Ibrahimi | Zendy; J C Picaud | Zendy; Saâd El Kabbaj | Zendy; François Vandenesch | Zendy; Frédéric Laurent | Zendy

Open Access

Characterization of a Novel Composite Staphylococcal Cassette Chromosome mec (SCC mec -SCC cad / ars / cop ) in the Neonatal Sepsis-Associated Staphylococcus capitis Pulsotype NRCS-A

Author(s) -

Patrícia Martins-Simões,

JeanPhilippe Rasigade,

Hajar Lemriss,

Marine Butin,

Christophe Ginévra,

Sanaâ Lemriss,

Richard V. Goering,

Azeddine Ibrahimi,

J C Picaud,

Saâd El Kabbaj,

François Vandenesch,

Frédéric Laurent

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01576-13

Subject(s) - sccmec , staphylococcus aureus , microbiology and biotechnology , biology , bacteremia , staphylococcus , mobile genetic elements , chromosome , sepsis , genetics , gene , bacteria , genome , methicillin resistant staphylococcus aureus , immunology , antibiotics

MultiresistantStaphylococcus capitis pulsotype NRCS-A has been reported to be a major pathogen causing nosocomial bacteremia in preterm infants. We report that the NRCS-A strain CR01 harbors a novel 60.9-kb composite staphylococcal cassette chromosomemec (SCCmec ) element, composed of an SCCmec with strong homologies toStaphylococcus aureus ST398 SCCmec and of an SCCcad/ars/cop harboring resistance genes for cadmium, arsenic, and copper. Whole-genome-based comparisons of publishedS. capitis strains suggest that strain CR01 acquired the two elements independently.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research