In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species | Zendy

Barbara Fiori | Zendy; Brunella Posteraro | Zendy; Riccardo Torelli | Zendy; Mario Tumbarello | Zendy; David S. Perlin | Zendy; Giovanni Fadda | Zendy; Maurizio Sanguinetti | Zendy

Open Access

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Author(s) -

Barbara Fiori,

Brunella Posteraro,

Riccardo Torelli,

Mario Tumbarello,

David S. Perlin,

Giovanni Fadda,

Maurizio Sanguinetti

Publication year - 2011

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01569-10

Subject(s) - anidulafungin , caspofungin , voriconazole , echinocandins , microbiology and biotechnology , fluconazole , amphotericin b , biology , echinocandin , fungi imperfecti , aspergillus , antifungal

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

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