Ceftobiprole Activity against Gram-Positive and -Negative Pathogens Collected from the United States in 2006 and 2016
Author(s) -
Michael A. Pfaller,
Robert K. Flamm,
Rodrigo E. Mendes,
Jennifer M Streit,
Jennifer I. Smart,
Kamal Hamed,
Leonard R Duncan,
Hélio S. Sader
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01566-18
Subject(s) - microbiology and biotechnology , moraxella catarrhalis , cephalosporin , enterococcus faecalis , biology , staphylococcus aureus , pseudomonas aeruginosa , streptococcus pneumoniae , haemophilus influenzae , klebsiella pneumoniae , acinetobacter baumannii , pneumonia , klebsiella pneumonia , antibiotics , medicine , escherichia coli , bacteria , biochemistry , genetics , gene
Ceftobiprole is an advanced cephalosporin with potent activity against Gram-positive and Gram-negative bacteria that has been approved in many European and non-European countries to treat community- and hospital-acquired pneumonia (excluding ventilator-associated pneumonia). This study reports on the activity of ceftobiprole against a large set of clinical isolates obtained from hospitalized patients in the United States in 2016 that caused serious infections, including pneumonia, bacteremia, and skin and skin structure infections.
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