Activity Profile In Vitro of Micafungin against Spanish Clinical Isolates of Common and Emerging Species of Yeasts and Molds
Author(s) -
Manuel CuencaEstrella,
Alicia GómezLópez,
Emilia Mellado,
Araceli Monzón,
María José Buitrago,
Juan L. Rodrı́guez-Tudela
Publication year - 2009
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01543-08
Subject(s) - micafungin , in vitro , microbiology and biotechnology , biology , yeast , antifungal , voriconazole , biochemistry
A collection of 2,278 isolates belonging to 86 different fungal species was tested with micafungin and eight other drugs using the EUCAST procedures. Micafungin was active against species of Candida and Aspergillus (even azole-resistant species) as well as Penicillium spp., Scedosporium apiospermum, and Acremonium spp. It was inactive for species of Basidiomycota and Mucorales and for multiresistant species such as those of Fusarium.
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