Prevalence of aac(6′)-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme among Enterobacteriaceae Blood Isolates in Korea | Zendy

Eun Sil Kim | Zendy; JinYong Jeong | Zendy; JaeBum Jun | Zendy; SangHo Choi | Zendy; SangOh Lee | Zendy; MiNa Kim | Zendy; Jun Hee Woo | Zendy; Yang Soo Kim | Zendy

Open Access

Prevalence of aac(6′)-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme among Enterobacteriaceae Blood Isolates in Korea

Author(s) -

Eun Sil Kim,

JinYong Jeong,

JaeBum Jun,

SangHo Choi,

SangOh Lee,

MiNa Kim,

Jun Hee Woo,

Yang Soo Kim

Publication year - 2009

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01534-08

Subject(s) - enterobacteriaceae , klebsiella pneumoniae , microbiology and biotechnology , enterobacter , ciprofloxacin , biology , escherichia coli , gene , genetics , antibiotics

Theaac(6′)-Ib gene was detected in 86 of 555 (15.5%)Enterobacteriaceae isolates. Among these 86aac(6′)-Ib -positive isolates, 19 (22.0%) were positive foraac(6′)-Ib-cr : 4 of 31 (12.9%)Enterobacter spp., 7 of 13 (53.8%)Escherichia coli isolates, and 8 of 42 (19.0%)Klebsiella pneumoniae isolates. There was a strong association betweenaac(6′)-Ib-cr and OXA-1 and CTX-M-1 group β-lactamase genes. Oneaac(6′)-Ib -positiveK. pneumoniae isolate carried bothaac(6′)-Ib-cr andqnrS .

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