Carbapenemase-Producing Enterobacteriaceae in Spain in 2012 | Zendy

Jesús Oteo | Zendy; David Saéz | Zendy; Verónica Bautista | Zendy; Sara Fernández-Romero | Zendy; Juan Manuel Hernández-Molina | Zendy; Marı́a Pérez-Vázquez | Zendy; Belén Aracil | Zendy; José Campos | Zendy

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Carbapenemase-Producing Enterobacteriaceae in Spain in 2012

Author(s) -

Jesús Oteo,

David Saéz,

Verónica Bautista,

Sara Fernández-Romero,

Juan Manuel Hernández-Molina,

Marı́a Pérez-Vázquez,

Belén Aracil,

José Campos

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01513-13

Subject(s) - klebsiella pneumoniae , multilocus sequence typing , enterobacteriaceae , microbiology and biotechnology , biology , bacterial protein , bacteria , escherichia coli , gene , genetics , genotype

We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1. Interhospital spread of carbapenemase-producing Klebsiella pneumoniae was due to a limited number of multilocus sequence types (MLST) and carbapenemase types, including ST15-VIM-1, ST11-OXA-48, ST405-OXA-48, ST101-KPC-2, and ST11-VIM-1. The number of CPE cases in Spain has increased sharply in recent years, due mainly to the emergence of OXA-48.

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