In Vitro Killing of Nosocomial Pathogens by Acid and Acidified Nitrite | Zendy

Agam Rao | Zendy; Robin Jump | Zendy; Nicole J. Pultz | Zendy; Michael J. Pultz | Zendy; Curtis J. Donskey | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

In Vitro Killing of Nosocomial Pathogens by Acid and Acidified Nitrite

Author(s) -

Agam Rao,

Robin Jump,

Nicole J. Pultz,

Michael J. Pultz,

Curtis J. Donskey

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01506-05

Subject(s) - microbiology and biotechnology , klebsiella pneumoniae , clostridium difficile , candida glabrata , enterococcus , staphylococcus aureus , nitrite , vancomycin , chemistry , in vitro , biology , bacteria , candida albicans , antibiotics , escherichia coli , nitrate , biochemistry , gene , genetics , organic chemistry

Exposure to pH 1 or 2 buffers or acidic gastric contents resulted in the killing of vancomycin-resistantEnterococcus sp.,Klebsiella pneumoniae ,Staphylococcus aureus , andCandida glabrata but notClostridium difficile spores. Nitrite enhanced killing under acidic conditions, but significant killing ofC. difficile spores required nitrite concentrations above usual physiological levels.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research