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Evaluation of Carbapenems for Treatment of Multi- and Extensively Drug-Resistant Mycobacterium tuberculosis
Author(s) -
Sander P. van Rijn,
Marlanka A. Zuur,
Richard Anthony,
Bob Wilffert,
Richard van Altena,
Onno W. Akkerman,
Wiel C.M. de Lange,
Tjip S. van der Werf,
Jos G.W. Kosterink,
JanWillem C. Alffenaar
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01489-18
Subject(s) - ertapenem , meropenem , mycobacterium tuberculosis , tuberculosis , medicine , carbapenem , imipenem , tolerability , regimen , intensive care medicine , antibiotics , microbiology and biotechnology , antibiotic resistance , biology , adverse effect , pathology
Multi- and extensively drug-resistant tuberculosis (M/XDR-TB) has become an increasing threat not only in countries where the TB burden is high but also in affluent regions, due to increased international travel and globalization. Carbapenems are earmarked as potentially active drugs for the treatment ofMycobacterium tuberculosis .

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