Staphylococcus aureus Strains That are Hypersusceptible to Resistance Gene Transfer from Enterococci | Zendy

Julia Marsh Sung | Zendy; Jodi A. Lindsay | Zendy

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Staphylococcus aureus Strains That are Hypersusceptible to Resistance Gene Transfer from Enterococci

Author(s) -

Julia Marsh Sung,

Jodi A. Lindsay

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01442-06

Subject(s) - staphylococcus aureus , microbiology and biotechnology , enterococcus faecalis , biology , vancomycin , enterococcus , drug resistance , mutant , gene , bacteria , antibiotics , genetics

We identified naturally occurring Staphylococcus aureus mutants of the restriction modification pathway SauI, including bovine lineage ST151. In a model of vancomycin resistance transfer from Enterococcus faecalis, ST151 isolates are 500 times more susceptible than human S. aureus isolates. The eradication of "hyperrecipient" strains may reduce the evolution of vancomycin-resistant S. aureus.

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