Identification of VIM-2-Producing Pseudomonas aeruginosa from Tanzania Is Associated with Sequence Types 244 and 640 and the Location of bla VIM-2 in a TniC Integron | Zendy

Sabrina J. Moyo | Zendy; Bjørg Haldorsen | Zendy; Said Aboud | Zendy; Bjørn Blomberg | Zendy; Samuel Y. Maselle | Zendy; Arnfinn Sundsfjord | Zendy; Nina Langeland | Zendy; Ørjan Samuelsen | Zendy

Open Access

Identification of VIM-2-Producing Pseudomonas aeruginosa from Tanzania Is Associated with Sequence Types 244 and 640 and the Location of bla _VIM-2 in a TniC Integron

Author(s) -

Sabrina J. Moyo,

Bjørg Haldorsen,

Said Aboud,

Bjørn Blomberg,

Samuel Y. Maselle,

Arnfinn Sundsfjord,

Nina Langeland,

Ørjan Samuelsen

Publication year - 2014

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01436-13

Subject(s) - pseudomonas aeruginosa , integron , biology , microbiology and biotechnology , identification (biology) , tanzania , sequence (biology) , genetics , bacteria , antibiotics , geography , antibiotic resistance , botany , environmental planning

Epidemiological data on carbapenemase-producing Gram-negative bacteria on the African continent are limited. Here, we report the identification of VIM-2-producing Pseudomonas aeruginosa isolates in Tanzania. Eight out of 90 clinical isolates of P. aeruginosa from a tertiary care hospital in Dar es Salaam were shown to harbor bla(VIM-2). The bla(VIM-2)-positive isolates belonged to two different sequence types (ST), ST244 and ST640, with bla(VIM-2) located in an unusual integron structure lacking the 3' conserved region of qacΔE1-sul1.

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